Digoxin Drug Interactions

Digoxin-1

Digoxin Major Interactions:

Digoxin + Clarithromycin:-

These Combinations of medicines together can affect the rhythm of your heart. Consult your doctor if you have uneven heartbeat, blurred vision, chest tightness,  seizures and nausea. You may need a dose adjustment or need your blood levels checked more often if you take both medications. It is vital to inform your doctor concerning all alternative medications you use.

Digoxin + Calcium Gluconate:-

These Combinations of drugs together can affect the rhythm of your heart. if you have any symptoms of irregular heartbeat, chest tightness, blurred vision, nausea, and seizures. You may need a dose adjustment or need your blood levels checked more often if you take both medications. It is vital to inform your doctor concerning all alternative medications you use.




Digoxin + Quinidine:-

These combinations of medications may significantly increase the blood levels and effects of digoxin. Consult your doctor if you experience nausea, vomiting, diarrhea, loss of appetite, visual disturbances an abnormally fast or slow heartbeat, as these may be signs and symptoms of excessive digoxin levels.

Digoxin +Arbutamine:-

Ask your Doctor before utilizing digoxin together with arbutamine. Utilizing these drugs together may cause a perilous reaction on your heart. In the event that your specialist endorses these drugs along, you may require a portion modification or extraordinary tests to securely take the two prescriptions.It is fundamental to illuminate your specialist concerning every single distinctive prescription you use.Try not to stop abuse any prescriptions while not contact your doctor.

Digoxin + Atazanavir:-

Utilizing atazanavir together with digoxin can build the danger of a sporadic heart mood that might be not kidding. You should chase for quick therapeutic consideration on the off chance that you create startling wooziness, dazedness, blacking out, or sporadic heartbeat all through treatment with these drug, regardless of whether along or alone. Try not to stop abuse any prescriptions while not contact your doctor.

Digoxin + Dolasetron:-

These Combination of meds can expand the danger of an unpredictable heart beat that might be counsel Your specialist in the event that you experience tipsiness, unsteadiness, blacking out, or sporadic heartbeat during treatment with these medications.

Digoxin + Itraconazole:-

These blend of medications increment the blood levels and impacts of digoxin.Contact your specialist on the off chance that you have any experience sickness, heaving, loose bowels, loss of hunger, visual unsettling influences, unusually quick or moderate heartbeat and you should and should utilize elective medication.

Digoxin Moderate Drug Interactions:-  

Digoxin + Azithriomycin:-

these combinations of medications may increase the blood levels and effects of digoxin. Consult your doctor if you experience nausea, vomiting, diarrhea, loss of appetite, visual disturbances an abnormally fast or slow or uneven heartbeat, as these may be signs and symptoms of excessive digoxin levels.

Digoxin + Atorvastatin:-

Consult your doctor  your doctor if you have experience of nausea, loss of appetite, uneven heartbeats or slow pulse rate, visual changes.

Digoxin + Atenolol:-

Consult your doctor if you have experience nausea, vomiting, decreased appetite, diarrhea, confusion, seizures, visual changes, fatigue, irregular heartbeats, and abnormally fast or slow heartbeats.

Digoxin + Aspirin:-

These combination of Dugs may increase digoxin levels. Consult your doctor  if you have experience of  nausea, loss of appetite, visual changes, slow pulse, or irregular heartbeats.

Digoxin + Alprazolam:-

These combination of Dugs may increase digoxin levels, Consult your doctor if you have experience nausea, vomiting, diarrhea, loss of appetite, visual disturbance an abnormally fast or slow heartbeat.

Digoxin+ Acetazolamide:-

Counsel your specialist on the off chance that you have any manifestations, for example, shortcoming, tiredness, muscle torments or issues, sickness, decline hunger, visual issues, or sporadic pulses.

Digoxin+ Benzthiazide:-

these blend of medications are regularly utilized together yet may require increasingly visit assessment of your digoxin, potassium, and magnesium levels. counsel your specialist on the off chance that you have any side effects, for example, shortcoming, tiredness, muscle torments or issues, sickness, decline craving, visual issues, or unpredictable pulses.

Digoxin+ Betamethasone:-

These blend of drug could cause expanded weight level, sporadic pulses, lightweight “coronas” around articles, unpracticed or yellow vision, weakness, swollen hands, feet, or lower legs (liquid maintenance). On the off chance that you take the two drugs together, counsel your specialist and  safely use both medicines.

Digoxin+ betaxolol:-

Betaxolol and digoxin may moderate your pulse and lead to expanded symptoms. Counsel your specialist if you have any experience sickness, heaving, diminished craving, the runs, disarray, seizures, visual changes, weakness, unpredictable pulses, and unusually quick or moderate pulses.

Digoxin+Calcitriol:-

calcitriol can expand the degrees of calcium in your body. since calcium can improve the impacts of digoxin on the heart, utilizing an excessive amount of calcitriol can cause digoxin poisonous quality and sporadic heartbeat. counsel your specialist in the event that you have any experience, for example, shortcoming, exhaustion, migraine, sluggishness, wooziness, ringing in the ears, loss of hunger, sickness, retching, clogging, dry mouth, a metallic preference for the mouth, bone or muscle torment, unskillfulness, visit end, and weight reduction.

Digoxin + Calcium acetate:-

 intemperate blood levels of calcium can build the impacts of digoxin. try not to surpass the dose of calcium acetic acid derivation endorsed by your specialist or prescribed on the item marking. you ought to likewise check with your specialist before utilizing any over-the-counter items that contain calcium, for example, nutrient enhancements or stomach settling agents.

Digoxin+ Calcium carbonate:-

over the top blood levels of calcium can expand the impacts of digoxin.try not to surpass the portion of carbonate recommended by your specialist or directed on the product marking. you ought to likewise check with your specialist before utilizing any over-the-counter items that contain calcium, for example, nutrient enhancements or stomach settling agents.

Digoxin + Calcium citrate:-

unnecessary blood levels of calcium can build the impacts of digoxin. try not to surpass the dose of calcium citrate endorsed by your specialist or suggested on the item marking. you ought to likewise check with your specialist before utilizing any over-the-counter items that contain calcium, for example, nutrient enhancements or stomach settling agents.

Digoxin+Captopril:-

captopril may expand the blood levels and impacts of digoxin. counsel your specialist on the off chance that you have any experience queasiness, regurgitating, loose bowels, loss of hunger, visual unsettling influences , anomalous quick or moderate heartbeat.

Digoxin+Chloroquine:-

Chloroquine may build the blood levels and impacts of digoxin. counsel your specialist in the event that you have any experience queasiness, heaving, loose bowels, loss of hunger, visual unsettling influences an anomalous quick or moderate heartbeat, as these might be signs and manifestations of inordinate digoxin levels.

Digoxin +Cholecalciferol:-

Cholecalciferol can build the degrees of calcium in your body. since calcium can upgrade the impacts of digoxin on the heart, utilizing a lot of cholecalciferol can cause digoxin harmfulness and sporadic heart musicality. contact your specialist on the off chance that you experience, for example, shortcoming, weakness, migraine, languor, wooziness, ringing in the ears, loss of hunger, sickness, regurgitating, clogging, dry mouth, a metallic preference for the mouth, bone or muscle torment, incoordination, visit pee, and weight reduction. you ought to likewise look for therapeutic consideration in the event that you experience indications of digoxin poisonous quality, for example, sickness, regurgitating, obscured vision, moderate heartbeat, or unpredictable pulses.

Digoxin+ Chlorthalidone:-

prior to taking chlorthalidone, tell your specialist in the event that you additionally use digoxin. chlorthalidone and digoxin are regularly utilized together however may require increasingly visit assessment of your digoxin, potassium, and magnesium levels. you ought to inform your specialist on the off chance that you have manifestations, for example, shortcoming, tiredness, muscle torments or spasms, queasiness, decline hunger, visual issues, or sporadic pulses. it is essential to educate your specialist concerning every single elective drug you utilize.

Digoxin +Clobazam:-

clobazam may build the blood levels and impacts of digoxin. . counsel your specialist in the event that you experience sickness, heaving, loose bowels, loss of craving, visual unsettling influences , an unusually quick or moderate heartbeat, as these might be signs and manifestations of inordinate digoxin levels.



Digoxin +Clonazepam:-

clonazepam may build the blood levels and impacts of digoxin. contact your specialist in the event that you experience sickness, regurgitating, looseness of the bowels, loss of hunger, visual aggravations , an anomalous quick or moderate heartbeat.

Digoxin+Clonidine:-

clonidine with digoxin may cause unreasonably low circulatory strain and pulse. counsel your specialist if your condition changes during treatment with these prescriptions.

Cyclosporine+Digoxin:-

digoxin with cyclosporine may build the impacts of digoxin. contact your specialist in the event that you experience sickness, heaving, diminished hunger, looseness of the bowels, disarray, seizures, visualizations, light “coronas” around items, green or yellow vision, weariness, sporadic pulses, and anomalous quick or moderate pulses.

Digoxin +Diazepam:-

Diazepam may increase the blood levels and effects of digoxin. Consult your doctor if you any experience nausea, vomiting, diarrhea, loss of appetence, visual disturbances (blurred vision; lightweight yellow vision), abnormally fast or slow heartbeat, as these may be signs and symptoms of excessive digoxin levels.

Digoxin+  Diclofenac:-

These combination of drugs may increase digoxin levels. contact your doctor if you have any experience of nausea, loss of appetite, visual changes, slow pulse, or irregular heartbeats.

 Digoxin+ Dopamine:-

Using digoxin and dopamine may  cause an irregular heart rhythm, since they can affect heart rate and blood pressure.

Digoxin+ doxycycline:-

These combination of drugs  may increase digoxin levels. Consult your doctor if you have any experience of  nausea, loss of appetite, visual changes, slow pulse, or irregular heartbeats.

Digoxin + VitaminD3:-

VitaminD3 can increase the levels of calcium in your body. Since calcium can enhance the effects of digoxin on the heart, using too much VitaminD3 can cause digoxin toxicity and irregular heart rhythm.

Consult your doctor if you experience symptoms that could indicate high blood calcium, such as weakness, fatigue, headache, drowsiness, dizziness, ringing in the ears, nausea ,loss of appetite, vomiting dry mouth ,constipation a pewter palate in the mouth, bone or muscle pain, incoordination, frequent urination, and weight loss.

You should also seek medical attention if you experience symptoms of digoxin toxicity such as nausea, vomiting, blurred vision, slow pulse, or irregular heartbeats. It is important to consult your doctor about all other medications you use.

Digoxin+Estazolam:-

Estazolam may increase the blood levels and effects of digoxin. Consult your doctor if you have any experience nausea, vomiting, diarrhea, loss of appetite, visual disturbances, an abnormally fast or slow heartbeat.

Digoxin+Esomeprazole:-

These combination of Drugs known as proton pump inhibitors including esomeprazole may increase the effects of digoxin. In the short-run, esomeprazole can occasionally cause an increase in the blood levels of digoxin.

You should seek immediate medical attention if you experience signs and symptoms that may indicate excessive effects of digoxin, such as nausea, vomiting, diarrhea, loss of appetite, visual disturbances an abnormally fast or slow heartbeat.

irregular heart rhythm, palpitations, muscle spasm, tremor, or seizures. In kids, abnormal rhythm could cause fatigue, stomach upset, dizziness, and lightheadedness.

Digoxin+ Erythromycin:-

Consult your doctor if you have any experience nausea, vomiting, diarrhea, loss of appetite, visual disturbances abnormally fast or slow heartbeat, as these may be signs and symptoms of excessive digoxin levels.

Dedigoxin+ furosemide:-

Furosemide and digoxin are used together but may require more frequent evaluation of your digoxin, potassium, and magnesium levels. Consult your doctor if you have symptoms, such as weakness, tiredness, muscle pains or cramps, visual harms ,nausea, uneven heartbeats or reduction appetite.

Digoxin+Fosinopril:-

Fosinopril may increase the blood levels and effects of digoxin. Consult your doctor if you have any experience nausea, vomiting, diarrhea, loss of appetite, visual disturbances, an abnormally fast or slow heartbeat, as these may be signs and symptoms of excessive digoxin levels.

Digoxin+Flurazepam:-

Flurazepam may increase the blood levels and effects of digoxin.You may want a dose adjustment or additional frequent observation by your doctor to securely use each medications.

Consult your doctor if you have got any experience nausea, vomiting, diarrhea, loss of appetence, visual disturbances, fast or slow heartbeat, as these may be signs and symptoms of excessive digoxin levels.

Digoxin+Glycerin:-

Glycerin and digoxin are used together but may require more frequent evaluation of your digoxin, potassium, and magnesium levels. consult your doctor if you have any symptoms, such as weakness, tiredness, muscle or cramps, visual harms ,nausea, uneven heartbeats or reduction appetite.

Digoxin+Galantamine:-

Galantamine can occasionally cause excessively slow heart rate and low blood pressure, and using it with digoxin may increase that risk. Consult your doctor if you have any experience dizziness, lightheadedness, fainting, or irregular heartbeat.

Digoxin+Hydrocortisone:-

These combination of druds may cause High blood pressure, irregular heartbeats, light “auras” around substances, yellow  or green vision. fatigue, swollen hands, feet, or ankles (fluid retention). These type of symptoms you are experienced consult your doctor

Digoxin+Hydroxychloroquine:-

Hydroxychloroquine may raises the blood stages and special effects of digoxin. Consult your doctor if you experience nausea, vomiting, diarrhea, loss of appetite, visual disturbances an abnormally fast or slow heartbeat.

Digoxin+Ibuprofen:-

This combination of drugs may increase digoxin levels. Consult your doctor if you have any experience of nausea, loss of appetite, visual changes, slow pulse, or irregular heartbeats.

Digoxin+ketoconazole:-

Ketoconazole may irregularly increase the blood levels and effects of digoxin. Consult your doctor if you have any experience of visual changes, nausea, loss of appetite, slow pulse, or uneven heartbeats.

Digoxin+ketoprofen:-

This combination of drugs may increase digoxin levels. Consult your doctor if you have any  experience of visual changes, nausea, loss of appetite, slow pulse, or uneven heartbeats.

Digoxin+Labetalol:-

labetalol with digoxin may decrease your heart rate and lead to increased side effects. Consult your doctor if you have any experience of visual changes, nausea, loss of appetite, slow pulse, or uneven heartbeats. and abnormally fast or slow heartbeats.



Digoxin+Lorazepam:-

use these Lorazepam may leisurely the blood levels and effects of digoxin. Consult your doctor if you have any experience of nausea, vomiting, diarrhea, of visual changes, nausea, loss of appetite, slow pulse, or uneven heartbeats.

Digoxin+Levothyroxine:-

This combination of drugs may cause a decrease in digoxin levels. The dosage of digoxin may need to be increased and consult your doctor.

Digoxin+Lansoprazole:-

these combination of Drugs known as proton pump inhibitors including lansoprazole can rise the special effects of digoxin. In the short-term, lansoprazole can rarely cause an increase in the blood levels of digoxin. Consult your doctor if you have any experience of visual changes, nausea, loss of appetite, slow pulse, or uneven heartbeats.

Digoxin+Lisinopril:-

Lisinopril may rise the blood levels and effects of digoxin. Consult your doctor if you have any experience of nausea, vomiting, diarrhea, Consult your doctor if you have any experience of visual changes, nausea, loss of appetite, slow pulse, or uneven heartbeats.

Digoxin+Levalbuterol:-

levalbuterol with digoxin may reduce the blood levels of digoxin. Levalbuterol may also decrease your potassium blood levels and put you at an enlarged danger of an uneven heart rhythm that may be serious and potentially dangerous.

You may be a lot of vulnerable if you have got a heart disease known as noninheritable long QT disorder, extra cardiac diseases, transmission irregularities, or electrolyte turbulences.The risk could exist even once levalbuterol or similar medications area unit given by oral inhalation directly into the lungs, and additional thus if these product area unit overused.

Consult your doctor if you have any symptoms like tipsiness, dizziness, shortness of breath, or heart palpitations.

 Digoxin+Labetalol:-

labetalol with digoxin may decrease your heart rate and lead to increased side effects. Consult your doctor if you have any experience of nausea, vomiting, decreased appetite, diarrhea, confusion, seizures, visual changes, fatigue, irregular heartbeats, and abnormally fast or slow heartbeats.

Digoxin+Lorazepam:-

Lorazepam may slow the blood levels and effects of digoxin. Consult your doctor if you have any experience of nausea, vomiting, diarrhea, visual disturbances, fast or slow heartbeat, loss of appetite.

Digoxin+Levothyroxine:-

This combination of drugs may cause a decrease in digoxin levels. The dosage of digoxin may need to be increased and consult your doctor.
Digoxin+Lisinopril:-

Lisinopril may rise the blood levels and effects of digoxin. Consult your doctor if you have any experience of vomiting, nausea, diarrhea, visual disturbances, fast or slow heartbeat, loss of appetite.

Digoxin+Mannitol:-

Mannitol and digoxin may require more frequent evaluation of your digoxin, potassium, and magnesium levels. Consult your doctor if you have any experience of weakness, tiredness, muscle pains or cramps, nausea, decrease appetite, visual problems, or irregular heartbeat.

Digoxin+Metformin:-

consult Your doctor if you have any experience of weakness, slow heart rate, amassed sleepiness, stomach pain, muscle pain, shortness of breath, fainting sensation light-headed ache.

Digoxin+Methotrexate:-

Some cancer drugs like methotrexate can cause damage to the intestinal lining and interfere with the absorption of digoxin. Blood levels and effects of digoxin may be reduced during chemotherapy. Consult your doctor if you have any experience of heart failure such as tiredness, swelling, fluid retention, sudden weight gain, difficulty breathing, shortness of lungful, uneven heartbeat, or chest pain.

Digoxin+Metoprolol:-

Consult your doctor if you have gotany expertise of nausea, vomiting,  reduced appetency, diarrhea, confusion, seizures, visual changes, fatigue, irregular heartbeats, and abnormally  slow or fast heartbeats.

Digoxin+Mefenamicacid:-

This combination of drugs may increase digoxin levels. consult Your doctor if you have any experience of nausea, loss of appetite, visual changes, slow pulse, or irregular heartbeats.

Digoxin+Oxazepam:-

Oxazepam can rises the blood stages and special effects of digoxin. Consult your doctor if you have any experience of nausea, loss of appetite, vomiting, diarrhea, visual disturbances, and uneven heartbeat.

Digoxin+Pantoprazole:-

These combination of Drugs known as proton pump inhibitors including pantoprazole may increase the effects of digoxin. In the short-term, pantoprazole can sometimes cause an increases in the blood levels of digoxin. Consult your doctor if you have any experience of nausea, loss of appetite, vomiting, diarrhea, visual disturbances, and uneven heartbeat.

Digoxin+Penbutolol:-

Consult your doctor if you have any experience of nausea, vomiting, decreased appetite, diarrhea, confusion, seizures, visual changes, fatigue, irregular heartbeats, and abnormally fast or slow heartbeats

Digoxin+Penicillamine:-

Penicillamine with digoxin may decreases the effects of digoxin. Consultt your doctor if you have any condition changes or if you have experience worsening of your heart symptoms.

Digoxin+Pindolol:-

Consult your doctor if you have any experience of seizures, nausea, vomiting, reduced appetite, diarrhea, confusion, visual changes, fatigue, irregular heartbeats.

Digoxin+Prednisone:-

This mix of medications could cause pulse level, irregular heartbeats, fatigue, swollen hands, feet, Consult your doctor if you have any experience of above situations.



Digoxin+Propranolol:-

Consult your doctor if you have any experience of nausea, vomiting, reduced appetite, diarrhea, visual changes, confusion, seizures, fatigue, irregular heartbeats.

Digoxin+Prednisolone:-

This combination of medicinemight cause raised pressure level, irregular heartbeats, light-weight “coronas” around substances,  fatigue, yellow vision, swollen hands, feet, or ankles. Consult your doctor if you have any experience of above situations.

Digoxin+Quinine:-

Consult your doctor if you have any expertiseof nausea, hallucinations, vomiting,  diarrhea, confusion, seizures lightweight  fatigue, yellow vision, uneven heartbeats.

Digoxin+Quinapril:-

Quinapril may raises the blood levels and special effects of digoxin. Consult your doctor if you have experience of nausea, loss of appetite, vomiting, diarrhea, visual disturbances, irregular heartbeat.

Digoxin+Ramipril:-

Ramipril may raise the blood levels and effects of digoxin Consult your doctor if you have any experience of loss of appetite, diarrhea, nausea, vomiting, visual disturbances irregular heartbeat.

Digoxin+Rifampin:-

these Combination of drugs may decrease the blood levels and special effects of digoxin. Consult your doctor if you have any disorder changes or you understanding a worsening of your heart indications.

Digoxin+salsalate:-

this combination of drugs may increase digoxin levels. Consult your doctor if you have any experience of visual changes, nausea, loss of appetite, irregular heartbeats, and slow pulse.

Digoxin+Sodium Salicylate:-

this combination of drugs may rise digoxin levels. Consult your doctor if you have any experience of visual changes, nausea, loss of appetite, irregular heartbeats, and slow pulse.

Digoxin+Telmisartan:-

This combination of drugs may increase digoxin levels. Consult your doctor if you have any experience of visual changes, nausea, loss of appetite, irregular heartbeats, and slow pulse.

Digoxin+Tetracycline:-

This combination of drugs may increase digoxin levels. Consult your doctor if you have any experience of visual changes, nausea, loss of appetite, irregular heartbeats, and slow pulse.

Drug – Diseases Interactions:-

Moderate- Interactions:-

Digoxin+Hyperthyroidism:-

Heart disappointment and additionally atrial arrhythmias coming about because of hypermetabolic or hyperdynamic states, for example, hyperthyroidism, hypoxia, or arteriovenous shunt are best overseen by treating the hidden condition.

Atrial arrhythmias related with hypermetabolic states are especially unmanageable to digoxin, potentially because of adjusted pharmacokinetics.

In particular, the evident volume of appropriation and renal disposal of the medication might be expanded, bringing about lower serum fixations. Treatment with digoxin ought to be directed mindfully in patients with hyperthyroidism.

Serum digoxin levels ought to be observed normally and measurement modifications might be expected optional to changes in their thyroid condition.

Digoxin+hypothyroidism:-

Hypothyroidism may lessen the necessities for digoxin because of diminished volume of appropriation and plasma leeway of the medication.

Treatment with digoxin ought to be started at lower measurements in patients with hypothyroidism to maintain a strategic distance from poisonous quality.

Serum digoxin levels ought to be checked consistently and measurements modifications might be expected optional to changes in thyroid condition.

Digoxin+Acute Myocardial Infraction:-

The utilization of inotropic medicates in certain patients with intense myocardial localized necrosis may prompt increments in myocardial oxygen request and lead to ischemia. Treatment with digoxin ought to be directed warily in these patients.

Major- Interactions:

Digoxin+Renal Dysfunction:-

Digoxin is basically disposed of by the kidney. Patients with renal hindrance might be at expanded hazard for digoxin poisonous quality, including ventricular arrhythmias and AV conduction aggravations, because of diminished medication freedom.

Treatment with digoxin ought to be directed warily in patients with debilitated renal capacity. Measurement modifications ought to be made by item bundle marking and patient traits, for example, age, perfect body weight, and other accompanying sickness states and drug utilization.

Measurements additions ought to be made all around steadily, since the end half-life might be drawn out in these patients and a more drawn out time frame is required to set up enduring state serum fixations than ordinary.

These patients ought to be observed intently for signs of harmfulness, and doses additionally balanced as fundamental. In the event that poisonous quality happens, clinicians ought to know that the antagonistic impacts may likewise be drawn out.

Digoxin+hypocalcemia:-

Hypocalcemia can invalidate the impacts of digoxin. The medication might be incapable in hypocalcemic patients until serum calcium levels are reestablished to ordinary. Reestablish serum calcium levels preceding starting treatment with digoxin to get greatest outcomes when utilizing digoxin.



Conclusion:-

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