Propranolol Drug Uses, Precautions, Side Effects, Drug Interactions ADR’s Full Information.

PROPRANOLOL Drug

Propranolol Drug , Generic/Brand Names, Propranolol/Side Effects Category, Propranolol/Indications,

Propranolol/Dosage, Propranolol/Mechanism of Action, Propranolol/Precautions

PROPRANOLOL

Propranolol-Tablets

Image source: Propranolol Tablets

Generic name: Propranolol

Brand name: Anol-20,Betabloc,Betapro, Betapro-SR, Ciplar,Carnol,Cardizole.

Category/class: Beta- blocker’s.

Propranolol Use: It decreases heart rate, force of contraction & cardiac output. On prolonged administration BP gradually falls in hypertensives but not in normotensives.

Indications:

Hypertension, Angina Pectoris, Cardiac Arrhythmias, Post Myocardial Infraction, Tachycardia, Migraine, Anxiety.



Doses:

(*TD = 3 Times a day*)

(*OD = Once a day*)

(*BD = Twice a day/2 times a day*)

Adult Dosage:-

Propranolol drug doses

Route of Administration:

May be taken with or without food— Oral, IV

Frequency: Once a day (OD), twice a day / 2 Times a day (BD), 3 Times a day (TD)

Pregnancy Category: C

 Lactation:-

Move into breast milk use with alert.

Contra-indications: Chronic Obstructive Pulmonary Disease (COPD), Asthma, Partial or complete heart block. Acute myocardial infarction, Cardiogenic shock, Congestive heart failure.

Precautions : Impaired renal & hepatic functions pregnancy, cardiac failure. Myocardial insufficiency, reduced cardiac reserve.

Side-effects: Tiredness, lack of drive, G.I.upsets,  nightmares forgetfulness, rarely hallucinations, muscle fatigue.



Mechanism of action:It is a selective beta-blocker that inhibits competition in response to beta1 and beta – adrenergic stimulation, thereby decreasing heart rate, myocardial contractility, BP and myocardial oxygen request. They reduce portal pressure by producing splanchnic vasoconstriction, thereby reducing portal blood flow.

Adverse drug reactions: Cardiogenic shock, Cognitive dysfunction, Bronchospasm, Angina, Arterial insufficiency, Hypotension, Bradycardia, Contact dermatitis, Hyperkalemia, Hyperlipidemia.

General Considerations:

»Advice Patient to take immediate-release tablets on empty stomach.

»Instruct caregiver to withhold dosing if child is vomiting or not feeding regularly.

»Counsel patient against sudden discontinuation of drug.

Monitoring Parameters:-

»ECG, Heart rate

»BP with IV administration

»Rena and Liver Function.

Drug-Drug Interactions:

Propranolol Major Interactions:

Popranolol+Formoterol:-

propranolol is often not suggested if you’ve got respiratory disorder a history of asthma or serious ceaseless obstructive pneumonic sickness copd .consult your doctor if you have any queries or complaints.

Methyldopa+Propranolol:-

These combination of drugs cause lead to a serious increase in your blood pressure. consult your doctor if you experience nausea, vomiting, sweating, flushing, stiff neck, headache, or heart palpitations.

Propranolol +Arbutamine:-

these combination of drugs  can affect the rhythm of your heart. Consult your doctor if you have experience of irregular heartbeat, chest tightness, blurred vision or nausea.

Read More Drug Interactions



Conclusion:-

I’m sharing about the basic knowledge and  The more you share knowledge , the more knowledge grows.

If you have any questions and complaints and more information for consult your “Family Doctor” or “Personal “Doctor”.

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