Propranolol Drug Uses, Precautions, Side Effects, Drug Interactions ADR’s Full Information.

Propranolol Drug , Generic/Brand Names, Propranolol/Side Effects Category, Propranolol/Indications,

Propranolol/Dosage, Propranolol/Mechanism of Action, Propranolol/Precautions

PROPRANOLOL

Image source: Propranolol Tablets

Generic name: Propranolol

Brand name: Anol-20,Betabloc,Betapro, Betapro-SR, Ciplar,Carnol,Cardizole.

Category/class: Beta- blocker’s.

Propranolol Use: It decreases heart rate, force of contraction & cardiac output. On prolonged administration BP gradually falls in hypertensives but not in normotensives.

Indications:

Hypertension, Angina Pectoris, Cardiac Arrhythmias, Post Myocardial Infraction, Tachycardia, Migraine, Anxiety.

Doses:

(*TD = 3 Times a day*)

(*OD = Once a day*)

(*BD = Twice a day/2 times a day*)

Adult Dosage:-

Route of Administration:

May be taken with or without food— Oral, IV

Frequency: Once a day (OD), twice a day / 2 Times a day (BD), 3 Times a day (TD)

Pregnancy Category: C

Lactation:-

Move into breast milk use with alert.

Contra-indications: Chronic Obstructive Pulmonary Disease (COPD), Asthma, Partial or complete heart block. Acute myocardial infarction, Cardiogenic shock, Congestive heart failure.

Precautions : Impaired renal & hepatic functions pregnancy, cardiac failure. Myocardial insufficiency, reduced cardiac reserve.

Side-effects: Tiredness, lack of drive, G.I.upsets, nightmares forgetfulness, rarely hallucinations, muscle fatigue.

Mechanism of action:It is a selective beta-blocker that inhibits competition in response to beta1 and beta – adrenergic stimulation, thereby decreasing heart rate, myocardial contractility, BP and myocardial oxygen request. They reduce portal pressure by producing splanchnic vasoconstriction, thereby reducing portal blood flow.

Adverse drug reactions: Cardiogenic shock, Cognitive dysfunction, Bronchospasm, Angina, Arterial insufficiency, Hypotension, Bradycardia, Contact dermatitis, Hyperkalemia, Hyperlipidemia.

General Considerations:

»Advice Patient to take immediate-release tablets on empty stomach.

»Instruct caregiver to withhold dosing if child is vomiting or not feeding regularly.

»Counsel patient against sudden discontinuation of drug.

Monitoring Parameters:-

»ECG, Heart rate

»BP with IV administration

»Rena and Liver Function.

Drug-Drug Interactions:

Propranolol Major Interactions:

Popranolol+Formoterol:-

propranolol is often not suggested if you’ve got respiratory disorder a history of asthma or serious ceaseless obstructive pneumonic sickness copd .consult your doctor if you have any queries or complaints.

Methyldopa+Propranolol:-

These combination of drugs cause lead to a serious increase in your blood pressure. consult your doctor if you experience nausea, vomiting, sweating, flushing, stiff neck, headache, or heart palpitations.

Propranolol +Arbutamine:-

these combination of drugs can affect the rhythm of your heart. Consult your doctor if you have experience of irregular heartbeat, chest tightness, blurred vision or nausea.

Conclusion:-

I’m sharing about the basic knowledge and The more you share knowledge , the more knowledge grows.

If you have any questions and complaints and more information for consult your “Family Doctor” or “Personal “Doctor”.

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